“CBD oil is most often used to treat and prevent seizures in patients diagnosed with Dravet Syndrome or infantile spasms,” said Dr. Jeffrey Shafer, pediatric neurologist at the Children’s Hospital of Los Angeles. “Dravet syndrome is a rare epileptic encephalopathy in children and may occur as a result of a medication, a toxin, or lack of a healthy immune system.
There’s no conclusive evidence that CBD oil increases or decreases seizures, but it’s worth noting that when I was researching CBD oil for my own epileptic patients, I read a lot of articles about the dangers of synthetic cannabinoids. It’s worth noting that the main active ingredient in most (though not all) CBD products is a psychoactive ingredient, which means it doesn’t have the same medical benefits of a plant-based CBD.
Of course, it is true that there are dangers of synthetic THC. However, I have had a number of epileptic patients who have taken CBD oil that have had a dramatic decrease in seizures. The main reason for this is that CBD has a more complex profile than THC. For example, the psychoactive effects of THC make it a stronger narcotic, but it also has a much lower affinity for receptors, so less of it gets to the brain than a lot of other cannabinoids.
Like most pharmaceutical drugs, the effects of cannabis oil are the result of how much of it is absorbed and how much is excreted. Because the THC in CBD doesn’t get converted into THC in the body, it actually has a much more complex profile, meaning that less THC goes to the brain than with THC containing pharmaceutical drugs. This explains why cannabis oil seems to have a far more profound effect on these epileptic patients, and why they are so grateful to have the oil.
The reason why we refer to them as “seizures” is because they are only able to control their movements when they are under the influence of cannabis oil. When they are not using cannabis oil, they continue to have seizures. Although more research is needed, some seem to believe that cannabis oil could be the answer to curing epilepsy, especially in children.
But cannabis oil can also cause a lot of other problems that can affect people with epilepsy. According to a study done on children with epilepsy, those on the highest dosage of cannabis oil were found to have a three times higher risk of being hospitalized for depression. This is because cannabis oil can also cause anxiety. A study is also being done on people with epilepsy who suffer from anxiety. The results are still not conclusive, but researchers think cannabis oil may be the culprit.
The study being done on people with anxiety involved a group of people who had epilepsy and found that those on the highest dosage of cannabis oil were more likely to be hospitalized for anxiety. That is, those on the highest dose of cannabis oil had a three times higher chance of being hospitalized for the anxiety of having epilepsy.
The study, however, was conducted in an animal model where the amount of oil injected into the brain was about half of what human trials usually involve. That means the human trials that were performed in the 1970’s were probably not as effective as they could have been. The results may have been a fluke because the animals were used to the high dose of cannabis, but the human trials may have been more effective than the animals.
Cbd oil is thought to work by reducing the levels of a chemical called CBDA, which is a precursor to the neurotransmitter GABA in the brain. The brain’s own natural CBDA is thought to be important in regulating the amount of neurotransmitters in the brain. A substance like THC, for instance, blocks GABA, but THC is metabolized differently than CBD, so THC has a different effect on GABA.
The researchers used rats with THC receptors, but there is no evidence that humans have CBDA receptors at all, so it is possible they used the THC of choice, and other humans may have CBD oil.